Start up your smoker and set/get it to a temperature of 250F, and add the wood chips. Hickory, mesquite, or maple wood chips all would work well.
In a small bowl, mix together the Cajun seasoning, salt, garlic powder, onion powder, and black pepper until evenly combined.
2 tsp Cajun seasoning, 1 tsp salt, 1 tsp garlic powder, 1 tsp onion powder, 1/2 tsp black pepper
Rub the spice mixture evenly out all over the chicken breasts.
4-5 boneless, skinless chicken breasts
Place chicken breasts in the smoker, directly on the grates. I recommend using tongs for this since the grates will be hot. Brush the chicken lightly with honey, and reserve the rest for later.
1/2 cup honey
Cook for 2 1/2 - 3 hours, or until the chicken reaches an internal temperature of 165F, basting it with honey every hour.
Carefully transfer the hot chicken from the smoker to a waiting serving plate, and brush it with honey one final time.
Serve and enjoy!